{{Rsnum
|rsid=4565946
|Gene=TPH2
|Chromosome=12
|position=71942989
|Orientation=plus
|GMAF=0.2998
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=TPH2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 26.5 | 45.1 | 28.3
| HCB | 48.2 | 46.0 | 5.8
| JPT | 43.4 | 45.1 | 11.5
| YRI | 84.2 | 15.1 | 0.7
| ASW | 77.2 | 17.5 | 5.3
| CHB | 48.2 | 46.0 | 5.8
| CHD | 53.2 | 40.4 | 6.4
| GIH | 39.6 | 46.5 | 13.9
| LWK | 78.2 | 20.0 | 1.8
| MEX | 50.0 | 46.6 | 3.4
| MKK | 62.8 | 34.0 | 3.2
| TSI | 33.7 | 42.6 | 23.8
| HapMapRevision=28
}}{{PMID|16146581}} [[rs4570625]] and [[rs4565946]] linked to the pathogenesis of early-onset [[obsessive compulsive disorder]]

{{PMID Auto
|PMID=19800079
|Title=Association of polymorphisms of the tryptophan hydroxylase 2 gene with risk for bipolar disorder or suicidal behavior
}}

{{PMID Auto
|PMID=16116490
|Title=Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in attention-deficit/hyperactivity disorder.
}}

{{PMID Auto
|PMID=17346350
|Title=Case-control and family-based association studies of candidate genes in autistic disorder and its endophenotypes: TPH2 and GLO1.
|OA=1
}}

{{PMID Auto
|PMID=20403506
|Title=Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study.
|OA=1
}}

{{PMID Auto
|PMID=21085052
|Title=Association study of tryptophan hydroxylase 2 gene polymorphisms in bipolar disorder patients with panic disorder comorbidity.
}}

{{PMID Auto
|PMID=21412658
|Title=Associations between polymorphic variants of the tryptophan hydroxylase 2 gene and obsessive-compulsive disorder.
}}

{{PMID Auto
|PMID=21873838
|Title=Association between tryptophan hydroxylase-2 gene and late-onset depression.
}}

[[Tourette's Syndrome]]

{{PMID Auto
|PMID=24458851
|Title=Tryptophan hydroxylase 2 gene polymorphisms in Japanese patients with medication overuse headaches
}}

{{PMID Auto
|PMID=22655589
|Title=Investigation of tryptophan hydroxylase 2 (TPH2) in schizophrenia and in the response to antipsychotics.
}}

{{PMID Auto
|PMID=22835848
|Title=Tryptophan hydroxylase 2 gene polymorphisms and poststroke anxiety disorders.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}