{{Rsnum
|rsid=4576240
|Gene=KIAA0319
|Chromosome=6
|position=24596250
|Orientation=plus
|GMAF=0.05831
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=KIAA0319
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 82.3 | 16.8 | 0.9
| HCB | 96.4 | 3.6 | 0.0
| JPT | 93.8 | 5.3 | 0.9
| YRI | 92.5 | 7.5 | 0.0
| ASW | 86.0 | 14.0 | 0.0
| CHB | 96.4 | 3.6 | 0.0
| CHD | 98.1 | 1.9 | 0.0
| GIH | 86.1 | 11.9 | 2.0
| LWK | 90.9 | 8.2 | 0.9
| MEX | 98.2 | 1.8 | 0.0
| MKK | 73.7 | 22.4 | 3.8
| TSI | 81.4 | 17.6 | 1.0
| HapMapRevision=28
}}{{Venter SNP
|rsid=4576240
|allele=G
|frequency=0.933
|uid=1103652809084
|type=homozygous_SNP
|hugo=KIAA0319
|ensembl gene=ENSG00000137261
|ensembl transcript=ENST00000378214
|sift=TOLERATED
|disease=Defects in KIAA0319 may be a cause of susceptibility to [[dyslexia]] (DYX2) (MIM:600202); also called reading disability. DYX2 is a relatively common, complex cognitive disorder that affects 5 per cent to 10 per cent of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational, and intellectual opportunities and in the absence of sensory or neurological disability.
}}

{{PMID Auto
|PMID=15514892
|Title=A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States.
|OA=1
}}

{{PMID Auto
|PMID=15717286
|Title=Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia.
|OA=1
}}

{{GET Evidence
|gene=KIAA0319
|aa_change=Thr97Pro
|aa_change_short=T97P
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4576240
|n_genomes=1
|n_genomes_annotated=0
|n_haplomes=2
|n_articles=0
|n_articles_annotated=0
|nblosum100=4
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}