{{Rsnum
|rsid=4608580
|Gene=VWA3B
|Chromosome=2
|position=98244594
|Orientation=plus
|GMAF=0.3949
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=VWA3B
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 23.1 | 43.1 | 33.8
| HCB | 2.2 | 42.2 | 55.6
| JPT | 2.3 | 36.4 | 61.4
| YRI | 11.9 | 42.4 | 45.8
| ASW | 0.0 | 0.0 | 0.0
| CHB | 2.2 | 42.2 | 55.6
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs4608580
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Smoking Initiation (p = 0.00007905; OR for minor allele C:0.817)
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164920579
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4608580
|overall_frequency_n=71
|overall_frequency_d=124
|overall_frequency=0.572581
|n_genomes=45
|n_genomes_annotated=0
|n_haplomes=66
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}