{{Rsnum
|rsid=4646312
|Gene=COMT
|Chromosome=22
|position=19960814
|Orientation=plus
|GMAF=0.3136
|Gene_s=COMT
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 18.6 | 46.0 | 35.4
| HCB | 10.9 | 51.8 | 37.2
| JPT | 12.4 | 44.2 | 43.4
| YRI | 0.7 | 25.2 | 74.1
| ASW | 0.0 | 26.3 | 73.7
| CHB | 10.9 | 51.8 | 37.2
| CHD | 7.3 | 42.2 | 50.5
| GIH | 12.0 | 42.0 | 46.0
| LWK | 0.9 | 20.2 | 78.9
| MEX | 6.9 | 37.9 | 55.2
| MKK | 3.3 | 34.4 | 62.3
| TSI | 19.6 | 52.9 | 27.5
| HapMapRevision=28
}}This is one of the SNPs reported by [[NutraHacker SNPs|NutraHacker]].

{{PMID Auto
|PMID=16848906
|Title=Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans.
|OA=1
}}

{{PMID Auto
|PMID=18574484
|Title=The complex global pattern of genetic variation and linkage disequilibrium at catechol-O-methyltransferase.
|OA=1
}}

{{PMID Auto
|PMID=19015200
|Title=Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer.
|OA=1
}}

{{PMID Auto
|PMID=19693267
|Title=Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.
|OA=1
}}

{{PMID Auto
|PMID=19772600
|Title=A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data.
|OA=1
}}

{{PMID Auto
|PMID=21423693
|Title=Effect sizes in experimental pain produced by gender, genetic variants and sensitization procedures.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}