{{Rsnum
|rsid=4657139
|Chromosome=1
|position=162060117
|Orientation=plus
|GMAF=0.4059
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 3.1 | 52.3 | 44.6
| HCB | 44.4 | 48.9 | 6.7
| JPT | 59.1 | 31.8 | 9.1
| YRI | 93.7 | 6.3 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 44.4 | 48.9 | 6.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID|19204306|OA=1
}} [[rs10494366]], [[rs4657139]] and [[rs16847548]] were significantly associated with adjusted QT interval in whites. relative hazard of SCD associated with each C allele at rs16847548 was 1.31. [[rs12567209]] was also independently associated with SCD in whites (relative hazard 0.57, 95% confidence interval 0.39 to 0.83, P=0.003). No significant associations observed in blacks.

{{PMID Auto
|PMID=20215044
|Title=Relationship of Common Candidate Gene Variants to Electrocardiographic T-Wave Peak to T-Wave End Interval and T-Wave Morphology Parameters
|OA=1
}}

{{PMID Auto
|PMID=20538168
|Title=Polymorphisms in the NOS1AP Gene Modulate QT Interval Duration and Risk of Arrhythmias in the Long QT Syndrome
}}

{{PMID Auto
|PMID=19019189
|Title=Common candidate gene variants are associated with QT interval duration in the general population.
|OA=1
}}

{{PMID Auto
|PMID=19180230
|Title=Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population.
|OA=1
}}

{{PMID Auto
|PMID=19822806
|Title=NOS1AP is a genetic modifier of the long-QT syndrome.
|OA=1
}}

{{PMID Auto
|PMID=22708720
|Title=Identification of a novel KCNQ1 mutation in a large Saudi family with long QT syndrome: clinical consequences and preventive implications.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}