{{Rsnum
|rsid=4657178
|Gene=NOS1AP
|Chromosome=1
|position=162240820
|Orientation=plus
|GMAF=0.3797
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=NOS1AP
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 54.0 | 40.7 | 5.3
| HCB | 25.5 | 49.6 | 24.8
| JPT | 26.5 | 46.9 | 26.5
| YRI | 36.1 | 54.4 | 9.5
| ASW | 36.8 | 42.1 | 21.1
| CHB | 25.5 | 49.6 | 24.8
| CHD | 23.6 | 57.5 | 18.9
| GIH | 29.0 | 48.0 | 23.0
| LWK | 37.3 | 53.6 | 9.1
| MEX | 53.4 | 32.8 | 13.8
| MKK | 40.4 | 46.2 | 13.5
| TSI | 44.6 | 44.6 | 10.9
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19305409
|Trait=QT interval
|Title=Common variants at ten loci modulate the QT interval duration in the QTSCD Study
|RiskAllele=T
|Pval=7E-33
|OR=2.19
|ORtxt=[1.76-2.62] ms increase
|OA=1
}}

{{PharmGKB
|RSID=rs4657178
|Name_s=
|Gene_s=NOS1AP
|Feature=
|Evidence=PubMed ID:19305409; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Common variants at ten loci modulate the QT interval duration in the QTSCD Study. (Initial Sample Size: 15,842 individuals; Replication Sample Size: up to 13,602 individuals); (Region: 1q23.3; Reported Gene(s): NOS1AP; Risk Allele: rs4657178-T); (p-value= 7E-33).This variant is associated with QT interval.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739902
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4657178
|overall_frequency_n=43
|overall_frequency_d=128
|overall_frequency=0.335938
|n_genomes=30
|n_genomes_annotated=0
|n_haplomes=33
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}