{{Rsnum
|rsid=4712652
|Gene=LINC00340
|Chromosome=6
|position=22078386
|Orientation=plus
|GMAF=0.2897
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CASC15
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 34.5 | 45.1 | 20.4
| HCB | 78.1 | 19.0 | 2.9
| JPT | 70.8 | 19.5 | 9.7
| YRI | 0.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 78.1 | 19.0 | 2.9
| CHD | 78.0 | 19.3 | 2.8
| GIH | 46.5 | 28.3 | 25.3
| LWK | 40.7 | 36.1 | 23.1
| MEX | 44.8 | 43.1 | 12.1
| MKK | 0.0 | 0.0 | 0.0
| TSI | 36.3 | 46.1 | 17.6
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs4712652
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19174833
|Annotation=The analyses of genome-wide association data from 1,380 Europeans with early-onset and morbid adult obesity and 1,416 age-matched normal-weight controls found an association of this variant (rs4712652) near PRL for risk of pooled childhood and adult severe obesity.
|Drugs=
|Drug Classes=
|Diseases=Obesity
|Curation Level=Curated
|PharmGKB Accession ID=PA162565814
}}

{{PMID Auto
|PMID=20846890
|Title=A common variant near the PRL gene is associated with increased adiposity in males
}}

{{PMID Auto
|PMID=19553259
|Title=Common body mass index-associated variants confer risk of extreme obesity.
|OA=1
}}

{{PMID Auto
|PMID=20127379
|Title=From monogenic to polygenic obesity: recent advances.
|OA=1
}}

{{PMID Auto
|PMID=22430306
|Title=Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4712652
|overall_frequency_n=76
|overall_frequency_d=128
|overall_frequency=0.59375
|n_genomes=48
|n_genomes_annotated=0
|n_haplomes=68
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}