{{Rsnum
|rsid=472112
|Gene=ARRB1
|Chromosome=11
|position=75310457
|Orientation=minus
|GMAF=0.3829
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=ARRB1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 27.4 | 53.1 | 19.5
| HCB | 51.8 | 40.1 | 8.0
| JPT | 48.7 | 44.2 | 7.1
| YRI | 73.5 | 24.5 | 2.0
| ASW | 50.9 | 40.4 | 8.8
| CHB | 51.8 | 40.1 | 8.0
| CHD | 60.6 | 31.2 | 8.3
| GIH | 32.7 | 42.6 | 24.8
| LWK | 44.5 | 48.2 | 7.3
| MEX | 15.5 | 55.2 | 29.3
| MKK | 44.2 | 44.9 | 10.9
| TSI | 31.4 | 46.1 | 22.5
| HapMapRevision=28
}}{{Report GE
|PubMed=
|Source=
|AffyProbeset=SNP_A-2271499
|AffyOrientation=same
|AlleleA=A
|AlleleB=G
|onGW5=1
|rsid=472112
|ancestral=A
|RiskPopulation=Caucasian
|RiskAllele=A
|CaseFreq=
|ControlFreq=
|OddsRatioHet=
|OddsRatioHom=
|OddsRatioAll=-
|Disease=Substance dependence, Nicotine
|DiseaseSymbol=SD-N
}}

rs472112 increases susceptibility to Substance dependence, Nicotine for carriers of the A allele [PMID ]

{{PMID|17579607}} Beta-arrestins 1 and 2 are associated with nicotine dependence in European American smokers.

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Affy500k}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}