{{Rsnum
|rsid=4758405
|Chromosome=11
|position=6303404
|Orientation=plus
|GMAF=0.5
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 15.9 | 53.1 | 31.0
| HCB | 30.1 | 46.3 | 23.5
| JPT | 22.1 | 54.9 | 23.0
| YRI | 38.8 | 46.9 | 14.3
| ASW | 31.6 | 52.6 | 15.8
| CHB | 30.1 | 46.3 | 23.5
| CHD | 0.0 | 0.0 | 0.0
| GIH | 9.3 | 39.2 | 51.5
| LWK | 40.4 | 48.6 | 11.0
| MEX | 24.6 | 52.6 | 22.8
| MKK | 42.6 | 45.8 | 11.6
| TSI | 16.7 | 46.1 | 37.3
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs4758405
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Current Smoking (p = 0.000008407;OR for minor allele A:1.266).
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164924515
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4758405
|overall_frequency_n=71
|overall_frequency_d=128
|overall_frequency=0.554688
|n_genomes=44
|n_genomes_annotated=0
|n_haplomes=58
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}