{{Rsnum
|rsid=4775041
|Chromosome=15
|position=58382496
|Orientation=plus
|GMAF=0.2112
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene=LOC102724766
|Gene_s=LOC102724766
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 7.8 | 40.6 | 51.6
| HCB | 4.4 | 28.9 | 66.7
| JPT | 7.1 | 35.7 | 57.1
| YRI | 1.6 | 9.5 | 88.9
| ASW | 0.0 | 0.0 | 0.0
| CHB | 4.4 | 28.9 | 66.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
[[rs4775041]] is a SNP located near the [[LIPC]] gene.

A study of metabolite concentrations in the blood of 284 adult males from Southern Germany determined that several SNPs were associated either directly with a metabolite range or with a ratio of metabolites. The rarer [[rs4775041]](G) allele was associated with increased phosphatidylethanolamine values. {{doi|10.1371/journal.pgen.1000282}}

[[Image:rs4775041_322x277.jpg|322px|thumb|left|]]

{{PMID Auto GWAS
|PMID=19043545
|Trait=Serum metabolites
|Title=Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum
|RiskAllele=
|Pval=1E-7
|OR=NR
|ORtxt=NR
|OA=1
}}
{{PMID Auto GWAS
|PMID=18193043
|Trait=HDL cholesterol
|Title=Newly identified loci that influence lipid concentrations and risk of coronary artery disease
|RiskAllele=C
|Pval=3.0000000000000003E-20
|OR=1.38
|ORtxt=[NR] mg/dl higher
}}

{{PharmGKB
|RSID=rs4775041
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19043545; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum. (Initial Sample Size: 284 males; Replication Sample Size: NR); (Region: 15q22.1; Reported Gene(s): LIPC; Risk Allele: rs4775041-?); (p-value= 0.0000001).This variant is associated with Serum metabolites.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740319
}}

{{PMID Auto
|PMID=18852197
|Title=Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
|OA=1
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{PMID Auto
|PMID=19060910
|Title=Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|OA=1
}}

{{PMID Auto
|PMID=19060911
|Title=Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
|OA=1
}}

{{PMID Auto
|PMID=19148283
|Title=Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.
|OA=1
}}

{{PMID Auto
|PMID=19299407
|Title=Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.
|OA=1
}}

{{PMID Auto
|PMID=19435741
|Title=Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.
|OA=1
}}

{{PMID Auto
|PMID=19656773
|Title=A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.
|OA=1
}}

{{PMID Auto
|PMID=19734193
|Title=Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population.
|OA=1
}}

{{PMID Auto
|PMID=20339536
|Title=Genome-wide association of lipid-lowering response to statins in combined study populations.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4775041
|overall_frequency_n=23
|overall_frequency_d=128
|overall_frequency=0.179688
|n_genomes=16
|n_genomes_annotated=0
|n_haplomes=18
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=23150898
|Title=Evaluation of seven common lipid associated loci in a large Indian sib pair study
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}