{{Rsnum
|rsid=4778138
|Gene=OCA2
|Chromosome=15
|position=28090674
|Orientation=plus
|GMAF=0.4467
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=OCA2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 78.8 | 21.2 | 0.0
| HCB | 9.0 | 37.3 | 53.7
| JPT | 12.0 | 35.2 | 52.8
| YRI | 4.9 | 45.1 | 50.0
| ASW | 12.5 | 51.8 | 35.7
| CHB | 9.0 | 37.3 | 53.7
| CHD | 9.3 | 30.6 | 60.2
| GIH | 29.3 | 45.5 | 25.3
| LWK | 6.4 | 39.4 | 54.1
| MEX | 49.1 | 40.4 | 10.5
| MKK | 4.5 | 36.8 | 58.7
| TSI | 50.5 | 43.6 | 5.9
| HapMapRevision=28
}}

{{doi|10.1371/journal.pgen.1000993}} [[freckling]]

{{omim
|desc=SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 1; SHEP1
|id=227220
|rsnum=4778138
}}

{{omim
|id=611409
|desc=OCA2 GENE
|rsnum=4778138
}}

{{omim
|id=611409
|rsnum=4778138
|variant=0013
}}

{{PMID Auto
|PMID=17236130
|Title=A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation.
|OA=1
}}

{{PMID Auto
|PMID=18252221
|Title=Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene.
|OA=1
}}

{{PMID Auto
|PMID=18252222
|Title=A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color.
|OA=1
}}

{{PMID Auto
|PMID=18483556
|Title=A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.
|OA=1
}}

{{PMID Auto
|PMID=18528436
|Title=Linkage and association analysis of spectrophotometrically quantified hair color in Australian adolescents: the effect of OCA2 and HERC2.
}}

{{PMID Auto
|PMID=18683857
|Title=Variants of the MATP/SLC45A2 gene are protective for melanoma in the French population.
}}

{{PMID Auto
|PMID=19472299
|Title=Genotyping of five single nucleotide polymorphisms in the OCA2 and HERC2 genes associated with blue-brown eye color in the Japanese population.
}}

{{PMID Auto
|PMID=20585627
|Title=Web-based, participant-driven studies yield novel genetic associations for common traits.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}