{{Rsnum
|rsid=4788102
|Gene=SH2B1
|Chromosome=16
|position=28862077
|Orientation=plus
|GMAF=0.2649
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SH2B1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 14.2 | 47.8 | 38.1
| HCB | 4.4 | 21.9 | 73.7
| JPT | 1.8 | 23.9 | 74.3
| YRI | 4.8 | 34.9 | 60.3
| ASW | 7.0 | 29.8 | 63.2
| CHB | 4.4 | 21.9 | 73.7
| CHD | 0.9 | 19.3 | 79.8
| GIH | 11.9 | 32.7 | 55.4
| LWK | 3.6 | 33.6 | 62.7
| MEX | 13.8 | 51.7 | 34.5
| MKK | 0.0 | 22.4 | 77.6
| TSI | 8.8 | 38.2 | 52.9
| HapMapRevision=28
}}association with [[obesity]] {{PMID|19079260}}

{{PMID Auto
|PMID=21907990
|Title=The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells
|OA=1
}}

{{PMID Auto
|PMID=17228025
|Title=The SH2B gene is associated with serum leptin and body fat in normal female twins.
|OA=1
}}

{{PMID Auto
|PMID=19478790
|Title=The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.
|OA=1
}}

{{PMID Auto
|PMID=23054017
|Title=The joint effect of cigarette smoking and polymorphisms on LRP5, LEPR, near MC4R and SH2B1 genes on metabolic syndrome susceptibility in Taiwan
}}

[[Obesity: Preliminary Research]]

[[Measures of Obesity]]

{{PMID Auto
|PMID=23424664
|Title=Study of 11 BMI-associated loci identified in GWAS for associations with central obesity in the Chinese children
|OA=1
}}

{{PMID Auto
|PMID=24103803
|Title=The SH2B1 obesity locus and abnormal glucose homeostasis: Lack of evidence for association from a meta-analysis in individuals of European ancestry
}}

{{PMID Auto
|PMID=24269186
|Title=An obesity genetic risk score is associated with metabolic syndrome in Chinese children
}}

{{PMID Auto
|PMID=23121087
|Title=Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}