{{Rsnum
|rsid=4799570
|Gene=DSG4
|Chromosome=18
|position=31406370
|Orientation=plus
|ReferenceAllele=A
|MissenseAllele=C
|GMAF=0.04086
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=DSG4,RP11-534N16.1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 0.0 | 20.7 | 79.3
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 5.3 | 94.7
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 5.0 | 95.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 7.1 | 92.9
| MKK | 0.0 | 0.0 | 0.0
| TSI | 1.0 | 13.9 | 85.1
| HapMapRevision=28
}}

{{Venter SNP
|rsid=4799570
|allele=C
|frequency=0.875
|uid=1103645166785
|type=homozygous_SNP
|hugo=DSG4
|ensembl gene=ENSG00000175065
|ensembl transcript=ENST00000308128
|sift=TOLERATED
|disease=DSG4 is one of the target molecules recognized by autoantibodies in patients with pemphigus vulgaris. Pemphigus vulgaris is a potentially lethal skin disease in which epidermal blisters occur as the result of the loss of cell-cell adhesion.
}}

{{GET Evidence
|gene=DSG4
|aa_change=Ile644Leu
|aa_change_short=I644L
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4799570
|overall_frequency_n=9975
|overall_frequency_d=10758
|overall_frequency=0.927217
|n_genomes=56
|n_genomes_annotated=0
|n_haplomes=105
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|nblosum100=-2
|autoscore=1
|n_web_uneval=1
}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Affy500k}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}