{{Rsnum
|rsid=4803455
|Gene=TGFB1
|Chromosome=19
|position=41345604
|Orientation=plus
|GMAF=0.4784
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=TGFB1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 26.8 | 45.5 | 27.7
| HCB | 19.7 | 51.1 | 29.2
| JPT | 23.0 | 45.1 | 31.9
| YRI | 40.4 | 39.0 | 20.5
| ASW | 37.5 | 46.4 | 16.1
| CHB | 19.7 | 51.1 | 29.2
| CHD | 13.8 | 38.5 | 47.7
| GIH | 22.8 | 48.5 | 28.7
| LWK | 38.5 | 43.1 | 18.3
| MEX | 10.3 | 58.6 | 31.0
| MKK | 32.7 | 51.9 | 15.4
| TSI | 15.7 | 48.0 | 36.3
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19365037
|Title=TGFB1 as a susceptibility gene for high myopia: a replication study with new findings
}}

The T allele appears to be protective against high [[myopia]].

{{PMID Auto
|PMID=21167485
|Title=A polymorphism in transforming growth factor-?1 is associated with carotid plaques and increased carotid intima-media thickness in older Chinese men: The Guangzhou Biobank Cohort Study-Cardiovascular Disease Subcohort
}}

{{PMID Auto
|PMID=18424453
|Title=Interaction between a novel TGFB1 haplotype and CFTR genotype is associated with improved lung function in cystic fibrosis.
|OA=1
}}

{{PMID Auto
|PMID=18670143
|Title=The association of transforming growth factor beta 1 gene polymorphisms with the emphysema phenotype of COPD in Japanese.
}}

{{PMID Auto
|PMID=21068203
|Title=Genetic variation in the TGF-beta signaling pathway and colon and rectal cancer risk.
|OA=1
}}

{{PMID Auto
|PMID=23059779
|Title=A Study of Ethnic Differences in TGFβ1 Gene Polymorphisms and Effects on the Risk of Radiation Pneumonitis in Non-Small-Cell Lung Cancer
}}

{{ClinVar
|ALT=A
|CAF=0.5216; 0.4784
|CHROM=19
|CLNALLE=1
|CLNHGVS=NC_000019.9:g.41851509C>A
|CLNSIG=1
|COMMON=1
|FwdALT=A
|FwdREF=C
|GENEINFO=TGFB1:7040
|GENE_ID=7040
|GENE_NAME=TGFB1
|REF=C
|RSPOS=41851509
|Reversed=0
|SAO=0
|SSR=0
|Tags=PM;PMC;SLO;INT;VLD;G5A;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD
|VC=SNV
|VP=0x05016808000117051f100100
|WGT=1
|dbSNPBuildID=111
|rsid=4803455
}}

{{PMID Auto GWAS
  |PMID=23793025
  |Trait=Migraine
  |Title=Genome-wide meta-analysis identifies new susceptibility loci for migraine.
  |RiskAllele=
  |Pval=8E-7
  |OR=1.05
  |ORtxt=[1.03-1.08]
  }}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}