{{Rsnum
|rsid=4845622
|Gene=IL6R
|Chromosome=1
|position=154438943
|Orientation=plus
|GMAF=0.3196
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=IL6R
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 41.6 | 45.1 | 13.3
| HCB | 35.3 | 49.3 | 15.4
| JPT | 42.5 | 42.5 | 15.0
| YRI | 88.4 | 10.9 | 0.7
| ASW | 67.9 | 32.1 | 0.0
| CHB | 35.3 | 49.3 | 15.4
| CHD | 33.3 | 44.4 | 22.2
| GIH | 46.5 | 49.5 | 4.0
| LWK | 84.5 | 15.5 | 0.0
| MEX | 29.3 | 37.9 | 32.8
| MKK | 78.8 | 19.2 | 1.9
| TSI | 34.7 | 51.5 | 13.9
| HapMapRevision=28
}}A study of 219 female [[melanoma]] patients and an equal number of controls concluded that 4 linked SNPs within the [[IL6R]] gene were associated with increased [[melanoma]] risk, but only when heterozygous. The odds ratio associated with the minor allele of this SNP, [[rs4845622]], was 1.69 (CI: 1.03-2.75). The 4 linked SNPs from identified in this study are: [[rs6684439]], [[rs4845618]], [[rs4845622]], and [[rs8192284]].{{PMID|18781131|OA=1
}}

{{PMID Auto
|PMID=18852330
|Title=Interleukin-6 receptor gene, plasma C-reactive protein, and diabetes risk in women.
|OA=1
}}

{{on chip | Illumina Human 1M}}