{{Rsnum
|rsid=4846049
|Gene=MTHFR
|Chromosome=1
|position=11790308
|Orientation=plus
|GMAF=0.3104
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=MTHFR
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 38.5 | 47.7 | 13.8
| HCB | 64.4 | 31.1 | 4.4
| JPT | 66.7 | 31.1 | 2.2
| YRI | 28.6 | 49.2 | 22.2
| ASW | 0.0 | 0.0 | 0.0
| CHB | 64.4 | 31.1 | 4.4
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=19593234
|Title=Association analyses suggest multiple interaction effects of the methylenetetrahydrofolate reductase polymorphisms on timing of menarche and natural menopause in white women
|OA=1
}}

{{PMID Auto
|PMID=22647417
|Title=The human MTHFR rs4846049 polymorphism increases coronary heart disease risk through modifying miRNA binding
}}

{{PMID Auto
|PMID=20962791
|Title=Methylenetetrahydrofolate reductase gene polymorphisms and cerebral palsy in Chinese infants.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}