{{Rsnum
|rsid=490683
|Chromosome=3
|position=172457284
|Orientation=plus
|GMAF=0.2902
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 6.2 | 49.2 | 44.6
| HCB | 15.6 | 51.1 | 33.3
| JPT | 9.1 | 54.5 | 36.4
| YRI | 4.8 | 47.6 | 47.6
| ASW | 0.0 | 0.0 | 0.0
| CHB | 15.6 | 51.1 | 33.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs490683
|Name_s=
|Gene_s=GHSR
|Feature=
|Evidence=PubMed ID:18698404
|Annotation=A study in 507 middle-aged overweight persons with impaired glucose tolerance participating found an association of this SNP in the promoter region of GHSR with several measures of glucose and insulin metabolism during the follow-up. This SNP may be a functional, since additional in vitro gelshift experiments showed differential protein binding between the alleles, with higher binding to the G-allele. The C-allele may disrupt a putative binding site for the TF nuclear factor 1.
|Drugs=
|Drug Classes=
|Diseases=Obesity
|Curation Level=Curated
|PharmGKB Accession ID=PA162191377
}}

{{PMID Auto
|PMID=22411573
|Title=Association of ghrelin receptor promoter polymorphisms with weight loss following Roux-en-Y gastric bypass surgery.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs490683
|overall_frequency_n=40
|overall_frequency_d=128
|overall_frequency=0.3125
|n_genomes=34
|n_genomes_annotated=0
|n_haplomes=40
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}