{{Rsnum
|rsid=4954449
|Gene=LCT
|Chromosome=2
|position=135817964
|Orientation=plus
|ReferenceAllele=A
|MissenseAllele=G
|GMAF=0.01882
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=LCT
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 100.0 | 0.0 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 89.6 | 9.7 | 0.7
| ASW | 82.5 | 17.5 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 82.7 | 16.4 | 0.9
| MEX | 98.2 | 1.8 | 0.0
| MKK | 84.6 | 15.4 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{Venter SNP
|rsid=4954449
|allele=C
|frequency=1
|uid=1103658227802
|type=homozygous_SNP
|hugo=LCT
|ensembl gene=ENSG00000115850
|ensembl transcript=ENST00000264162
|sift=TOLERATED
|disease=Defects in the upstream vicinity of LCT are the cause of disaccharide intolerance III (MIM:223100); also known as adult lactase deficiency or adult-type hypolactasia. In many human populations the activity of LCT declines in adults, leading to adult-type hypolactasia, whereas in other populations the high activity persists.
}}

{{GET Evidence
|gene=LCT
|aa_change=Ile362Val
|aa_change_short=I362V
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4954449
|overall_frequency_n=10506
|overall_frequency_d=10758
|overall_frequency=0.976576
|n_genomes=56
|n_genomes_annotated=0
|n_haplomes=108
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|nblosum100=-4
|autoscore=2
|n_web_uneval=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}