{{Rsnum
|rsid=4977756
|Gene=CDKN2BAS
|Chromosome=9
|position=22068653
|Orientation=plus
|GMAF=0.3049
|Gene_s=CDKN2B-AS1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}[[rs4977756]] is a SNP near the [[CDKN2BAS]] gene.

A (GWA) study for open-angle [[glaucoma]] (OAG) blindness ultimately based on ~1500 cases concluded that the rather common [[rs4977756]](A) allele was statistically associated with the condition, with a per allele odds ratio of 1.39 (CI: 1.28–1.51, p = 1.35 × 10e?14).{{PMID|21532571}}

{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 34.5 | 47.8 | 17.7
| HCB | 61.9 | 32.1 | 6.0
| JPT | 61.3 | 30.6 | 8.1
| YRI | 43.8 | 47.9 | 8.2
| ASW | 47.4 | 49.1 | 3.5
| CHB | 61.9 | 32.1 | 6.0
| CHD | 63.0 | 33.3 | 3.7
| GIH | 40.6 | 48.5 | 10.9
| LWK | 40.4 | 46.8 | 12.8
| MEX | 71.9 | 26.3 | 1.8
| MKK | 24.0 | 49.4 | 26.6
| TSI | 41.2 | 52.0 | 6.9
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19578367
|Trait=Glioma
|Title=Genome-wide association study identifies five susceptibility loci for glioma
|RiskAllele=G
|Pval=7E-15
|OR=1.24
|ORtxt=[1.19-1.30]
}}

{{PMID Auto
|PMID=20462933
|Title=Interaction between 5 genetic variants and allergy in glioma risk
}}
{{PMID Auto
|PMID=20847058
|Title=Genetic risk profiles identify different molecular etiologies for glioma
|OA=1
}}
{{PMID Auto
|PMID=20211558
|Title=Genetic advances in glioma: susceptibility genes and networks
|OA=1
}}

{{omim
|id=613030
|rsnum=4977756
}}

{{PMID Auto
|PMID=19578366
|Title=Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
|OA=1
}}

{{PMID Auto
|PMID=20212223
|Title=New insights into susceptibility to glioma.
}}

{{PMID Auto
|PMID=21825990
|Title=Genetic causes of glioma: new leads in the labyrinth.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4977756
|overall_frequency_n=85
|overall_frequency_d=128
|overall_frequency=0.664062
|n_genomes=51
|n_genomes_annotated=0
|n_haplomes=76
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=22886559
  |Trait=Glioma
  |Title=Genome-wide association study of glioma and meta-analysis.
  |RiskAllele=G
  |Pval=1E-8
  |OR=1.28
  |ORtxt=[1.177-1.398]
  |OA=1
}}

{{PMID Auto
|PMID=23115063
|Title=Known glioma risk loci are associated with glioma with a family history of brain tumours -- a case-control gene association study
|OA=1
}}

{{PMID Auto
|PMID=23161787
|Title=Association between glioma susceptibility loci and tumour pathology defines specific molecular etiologies
|OA=1
}}

{{PMID Auto
|PMID=25165198
|Title=Mutation-based molecular glioma classification: prevalence and association with germline risk snps
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}