{{Rsnum
|rsid=4987076
|Gene=NAT1
|Chromosome=8
|position=18222492
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.01607
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=NAT1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 4.6 | 95.4
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 1.6 | 98.4
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
{{omim
|desc=NAT1*17 ALLELE
|id=108345
|rsnum=4987076
|variant=0002
}}

{{ClinVar
|rsid=4987076
|Reversed=0
|FwdREF=G
|FwdALT=A
|REF=G
|ALT=A
|RSPOS=18080001
|CHROM=8
|GMAF=0.016
|dbSNPBuildID=113
|SSR=0
|SAO=1
|VP=0x050378000000140517110100
|GENEINFO=NAT1:9
|GENE_NAME=NAT1
|GENE_ID=9
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000008.10:g.18080001G>A
|CLNORIGIN=1
|CLNSIG=5
|Tags=PM;TPA;PMC;S3D;SLO;VLD;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.9839; 0.01607
|CLNACC=RCV000019386.26
|CLNDBN=NAT1*17 ALLELE
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=108345.0002
|COMMON=1
|Disease=NAT1*17 ALLELE
}}

{{PMID Auto
|PMID=16112301
|Title=NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses.
|OA=1
}}

{{PMID Auto
|PMID=16416399
|Title=Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.
|OA=1
}}

{{PMID Auto
|PMID=16847422
|Title=Genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2) and risk of non-Hodgkin lymphoma.
|OA=1
}}

{{PMID Auto
|PMID=21290563
|Title=Functional effects of genetic polymorphisms in the N-acetyltransferase 1 coding and 3' untranslated regions.
|OA=1
}}

{{GET Evidence
|gene=NAT1
|aa_change=Val149Ile
|aa_change_short=V149I
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4987076
|overall_frequency_n=4
|overall_frequency_d=128
|overall_frequency=0.03125
|n_genomes=3
|n_genomes_annotated=0
|n_haplomes=3
|n_articles=0
|n_articles_annotated=0
|in_omim=Y
|pph2_score=0.001
|nblosum100=-4
|autoscore=2
|webscore=N
|n_web_uneval=9
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}