{{Rsnum
|rsid=499818
|Chromosome=6
|position=13332235
|Orientation=plus
|GMAF=0.1873
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 5.3 | 31.0 | 63.7
| HCB | 2.2 | 21.3 | 76.5
| JPT | 1.8 | 18.6 | 79.6
| YRI | 0.0 | 13.6 | 86.4
| ASW | 0.0 | 33.3 | 66.7
| CHB | 2.2 | 21.3 | 76.5
| CHD | 1.8 | 20.2 | 78.0
| GIH | 22.8 | 44.6 | 32.7
| LWK | 0.9 | 23.6 | 75.5
| MEX | 15.5 | 37.9 | 46.6
| MKK | 0.0 | 11.5 | 88.5
| TSI | 8.8 | 36.3 | 54.9
| HapMapRevision=28
}}

{{GWAS Summary
|SNP=rs499818
|PubMedID=17903304
|Condition=Major CVD
|Gene=Intergenic
|Risk Allele=
|pValue=7.00E-006
|OR=NA
|95CI=
|OA=1
}}

{{PharmGKB
|RSID=rs499818
|Name_s=
|Gene_s=TBC1D7
|Feature=
|Evidence=PubMed ID:17903304; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes (Initial Sample Size: 1,341-1,345 individuals, depending on measure (Framingham); Replication Sample Size: NR). This variant is associated with Major CVD.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356431
}}

{{PMID Auto
|PMID=22856164
|Title=[Evaluation of association between 9 genetic polymorphism and myocardial infarction in the Siberian population]
}}

{{PMID Auto
|PMID=20823317
|Title=is-rSNP: a novel technique for in silico regulatory SNP detection.
|OA=1
}}

{{PMID Auto
|PMID=22042884
|Title=Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs499818
|overall_frequency_n=26
|overall_frequency_d=128
|overall_frequency=0.203125
|n_genomes=16
|n_genomes_annotated=0
|n_haplomes=20
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=24087953
|Title=[Genetic predictors of myocardial infarction in subjects of young age]
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}