{{Rsnum
|rsid=501120
|Chromosome=10
|position=44753867
|Orientation=minus
|GMAF=0.2833
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 64.6 | 33.8 | 1.5
| HCB | 42.2 | 44.4 | 13.3
| JPT | 43.2 | 40.9 | 15.9
| YRI | 28.6 | 47.6 | 23.8
| ASW | 0.0 | 0.0 | 0.0
| CHB | 42.2 | 44.4 | 13.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}[[rs501120]] is a SNP found to be associated with [[heart disease]] in two populations by the German MI (Myocardial infarction) Family Study group. The risk allele in dbSNP orientation is [[rs501120]](A). The odds ratio per allele is 1.33 (CI: 1.20-1.48, adjusted p=0.0248).{{PMID|17634449|OA=1
}}

{{PMID Auto
|PMID=19164808
|Title=Large scale association analysis of novel genetic loci for coronary artery disease
|OA=1
}}
{{PMID Auto
|PMID=19955471
|Title=Genetic Variants Identified in a European Genome-Wide Association Study That Were Found to Predict Incident Coronary Heart Disease in the Atherosclerosis Risk in Communities Study
|OA=1
}}
{{PMID Auto
|PMID=20694560
|Title=Common genetic polymorphisms in Moyamoya and atherosclerotic disease in Europeans
}}
{{PMID Auto
|PMID=21415067
|Title=The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels
|OA=1
}}
{{PMID Auto
|PMID=22386691
|Title=Lack of association between the CXCL12 rs501120 polymorphism and cardiovascular disease in Spanish patients with rheumatoid arthritis.
}}

{{PMID|18780302|OA=1
}} Association studies of 22 candidate SNPs with late-onset Alzheimer's disease.

{{PMID|18979498|OA=1
}} The impact of newly identified loci on coronary heart disease, stroke and total mortality in the MORGAM prospective cohorts.

{{PMID|19750184|OA=1
}} Genome-wide association studies for atherosclerotic vascular disease and its risk factors.

{{PMID|19956433|OA=1
}} Genetics of coronary artery disease: focus on genome-wide association studies.

{{PMID|20017983|OA=1
}} Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.

{{PMID|20098575|OA=1
}} Genetics and cardiovascular disease: Design and development of a DNA biobank.

{{PMID|20847302}} Coronary artery disease-related genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis.

{{PMID|21242481|OA=1
}} Genetic risk score and risk of myocardial infarction in Hispanics.

{{PMID|21804106|OA=1
}} Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.

{{PMID|22042884|OA=1
}} Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study.
{{PMID Auto
|PMID=23666823
|Title=Genetic variants on chromosome 10q11.21 are associated with ischemic stroke in the northern Chinese Han population.
}}

{{PMID Auto GWAS
  |PMID=17634449
  |Trait=Coronary heart disease
  |Title=Genomewide association analysis of coronary artery disease. 
  |RiskAllele=T
  |Pval=9E-8
  |OR=1.33
  |ORtxt=[1.20-1.48]
  }}

{{PMID Auto GWAS
  |PMID=24262325
  |Trait=Coronary artery disease
  |Title=Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
  |RiskAllele=C
  |Pval=2E-6
  |OR=1.09
  |ORtxt=[1.05-1.14]
  }}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs501120
|overall_frequency_n=43
|overall_frequency_d=128
|overall_frequency=0.335938
|n_genomes=29
|n_genomes_annotated=0
|n_haplomes=38
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}