{{Rsnum
|rsid=5029937
|Gene=TNFAIP3
|Chromosome=6
|position=137874014
|Orientation=plus
|GMAF=0.124
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=TNFAIP3
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 92.3 | 7.7 | 0.0
| HCB | 82.2 | 17.8 | 0.0
| JPT | 64.4 | 31.1 | 4.4
| YRI | 22.2 | 57.1 | 20.6
| ASW | 0.0 | 0.0 | 0.0
| CHB | 82.2 | 17.8 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID|19417005|OA=1
}} [[rheumatoid arthritis]]
*[[rs6920220]] [P= 2.6 x 10(-6), OR 1.22 (1.13-1.33)]. 
*[[rs5029937]]
*[[rs13207033]] protective [P= 0.0001, OR 0.86 (0.8-0.93)] perfectly correlated with [[rs10499194]]
The combination of the carriage of both risk alleles of rs6920220 and rs5029937 together with the absence of the protective allele of rs13207033 was strongly associated with RA when compared to carriage of none [OR of 1.86 (95% CI) (1.51-2.29)]. This equates to an effect size of 1.50 (95% CI 1.21-1.85)

{{PMID Auto
|PMID=20498205
|Title=Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers
|OA=1
}}

{{omim
|id=180300
|rsnum=5029937
}}

{{omim
|id=612378
|rsnum=5029937
}}

{{PMID Auto
|PMID=19387456
|Title=Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.
|OA=1
}}

{{PMID Auto
|PMID=19838195
|Title=A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.
|OA=1
}}

{{PMID Auto
|PMID=20444755
|Title=Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.
|OA=1
}}

{{PMID Auto
|PMID=22328738
|Title=Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.
|OA=1
}}

{{PMID Auto
|PMID=22798268
|Title=Rheumatoid arthritis-associated polymorphisms at 6q23 are associated with radiological damage in autoantibody-positive RA.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}