{{Rsnum
|rsid=5030878
|Gene=FPR1
|Chromosome=19
|position=51746963
|Orientation=minus
|GMAF=0.1736
|Gene_s=FPR1,LOC100287831
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 63.7 | 31.0 | 5.3
| HCB | 88.2 | 11.8 | 0.0
| JPT | 97.3 | 2.7 | 0.0
| YRI | 68.0 | 27.2 | 4.8
| ASW | 57.9 | 40.4 | 1.8
| CHB | 88.2 | 11.8 | 0.0
| CHD | 92.6 | 6.5 | 0.9
| GIH | 80.0 | 17.0 | 3.0
| LWK | 56.4 | 37.3 | 6.4
| MEX | 73.7 | 24.6 | 1.8
| MKK | 58.4 | 33.1 | 8.4
| TSI | 56.9 | 41.2 | 2.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs5030878
|Name_s=FPR1: 32C>T; I11T; Ile11Thr
|Gene_s=FPR1
|Feature=
|Evidence=PubMed ID:19530962
|Annotation=This variant was associated with decreased soluble E-selectin levels in a study of 325 French adults from the STANISLAS cohort. The serum E-selectin levels were 68% lower in individuals homozygous for T/T than in those with C/T or C/C genotypes. This variant does not affect FPR1 mRNA expression. No significant association was found for this variant with C-reactive protein level in this study.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164920435
}}

{{PharmGKB
|RSID=rs5030878
|Name_s=FPR1: 32C>T; I11T; Ile11Thr
|Gene_s=FPR1
|Feature=
|Evidence=PubMed ID:16953235
|Annotation=Individuals homozygous for T/T exhibited elevated serum concentrations of C-reactive protein, increased absolute counts of blood leukocytes and neutrophils, and erythrocyte sedimentation rates.
|Drugs=
|Drug Classes=
|Diseases=Inflammation
|Curation Level=Curated
|PharmGKB Accession ID=PA164920436
}}

{{PMID Auto
|PMID=21144844
|Title=Human formyl peptide receptor 1 C32T SNP interacts with age and is associated with blood pressure levels.
}}

{{GET Evidence
|gene=FPR1
|aa_change=Ile11Thr
|aa_change_short=I11T
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs5030878
|overall_frequency_n=8317
|overall_frequency_d=10758
|overall_frequency=0.773099
|n_genomes=52
|n_genomes_annotated=0
|n_haplomes=84
|n_articles=2
|n_articles_annotated=2
|in_pharmgkb=Y
|nblosum100=3
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23373827
|Title=V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins.
|OA=1
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}