{{Rsnum
|rsid=509035
|Gene=GHSR
|Chromosome=3
|position=172445659
|Orientation=plus
|GMAF=0.2727
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=GHSR
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 8.0 | 43.4 | 48.7
| HCB | 24.8 | 43.8 | 31.4
| JPT | 13.3 | 50.4 | 36.3
| YRI | 0.0 | 8.2 | 91.8
| ASW | 0.0 | 12.3 | 87.7
| CHB | 24.8 | 43.8 | 31.4
| CHD | 22.9 | 43.1 | 33.9
| GIH | 3.0 | 30.7 | 66.3
| LWK | 0.0 | 10.9 | 89.1
| MEX | 8.6 | 46.6 | 44.8
| MKK | 0.6 | 19.2 | 80.1
| TSI | 4.9 | 35.3 | 59.8
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs509035
|Name_s=
|Gene_s=GHSR
|Feature=
|Evidence=PubMed ID:15616037; PubMed ID:18698404
|Annotation=A study in 507 middle-aged overweight persons with impaired glucose tolerance participating found an association of this SNP in the promoter region of GHSR with several measures of glucose and insulin metabolism during the follow-up. An association between this SNP and obesity was found in a study in 178 pedigrees with multiple obese members (DNA of 1,095 Caucasians) and in an independent sample of the general population (MONICA Augsburg left ventricular hypertrophy substudy; DNA of 1,418 Caucasians).
|Drugs=
|Drug Classes=
|Diseases=Obesity
|Curation Level=Curated
|PharmGKB Accession ID=PA162191378
}}

{{PMID Auto
|PMID=19593725
|Title=Association of maternally inherited GNAS alleles with African-American male birth weight.
|OA=1
}}

{{PMID Auto
|PMID=20404923
|Title=Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity.
|OA=1
}}

{{PMID Auto
|PMID=21269581
|Title=Analysis of the influence of the ghrelin receptor rs509035, rs512692 and rs2922126 polymorphisms in the risk of cardiovascular disease in patients with rheumatoid arthritis.
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs509035
|overall_frequency_n=26
|overall_frequency_d=126
|overall_frequency=0.206349
|n_genomes=22
|n_genomes_annotated=0
|n_haplomes=26
|n_articles=0
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}