{{Rsnum
|rsid=532964
|Gene=DMGDH
|Chromosome=5
|position=79044463
|Orientation=minus
|ReferenceAllele=T
|MissenseAllele=C
|GMAF=0.3921
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=DMGDH
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 20.5 | 53.6 | 25.9
| HCB | 64.2 | 33.6 | 2.2
| JPT | 53.6 | 41.1 | 5.4
| YRI | 43.5 | 45.6 | 10.9
| ASW | 29.8 | 50.9 | 19.3
| CHB | 64.2 | 33.6 | 2.2
| CHD | 61.5 | 33.9 | 4.6
| GIH | 31.7 | 46.5 | 21.8
| LWK | 34.5 | 47.3 | 18.2
| MEX | 29.8 | 61.4 | 8.8
| MKK | 27.7 | 55.5 | 16.8
| TSI | 21.6 | 54.9 | 23.5
| HapMapRevision=28
}}

{{Venter SNP
|rsid=532964
|allele=G
|frequency=0.467
|uid=1103654141733
|type=homozygous_SNP
|hugo=DMGDH
|ensembl gene=ENSG00000132837
|ensembl transcript=ENST00000255189
|sift=TOLERATED
|disease=Defects in DMGDH are the cause of DMGDH deficiency (DMGDHD) (MIM:605850). DMGDHD is a disorder characterized by fish odor, muscle fatigue with increased serum creatine kinase. Biochemically it is characterized by an increase of N,N- dimethylglycine (DMG) in serum and urine.
}}

{{PMID Auto
|PMID=19048631
|Title=Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study.
|OA=1
}}

{{GET Evidence
|gene=DMGDH
|aa_change=Ser279Pro
|aa_change_short=S279P
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs532964
|overall_frequency_n=5925
|overall_frequency_d=10758
|overall_frequency=0.550753
|n_genomes=44
|n_genomes_annotated=0
|n_haplomes=62
|n_articles=0
|n_articles_annotated=0
|nblosum100=3
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}