{{Rsnum
|rsid=5335
|Gene=EDNRA
|Chromosome=4
|position=147542688
|Orientation=plus
|GMAF=0.4986
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=EDNRA
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 18.8 | 50.0 | 31.2
| HCB | 15.6 | 53.3 | 31.1
| JPT | 22.2 | 48.9 | 28.9
| YRI | 49.2 | 44.4 | 6.3
| ASW | 0.0 | 0.0 | 0.0
| CHB | 15.6 | 53.3 | 31.1
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}[[rs5335]], a SNP in the [[EDNRA]] gene, has been associated with a (slightly) increased risk for [[hypertension]], based on a study of ~1400 Caucasians. The odds ratio per (G) allele is 1.19 (CI: 1.00-1.41, p=0.05).{{PMID|18172451}}

{{PMID Auto
|PMID=20028935
|Title=EDNRA variants associate with smooth muscle mRNA levels, cell proliferation rates and cystic fibrosis pulmonary disease severity
|OA=1
}}

{{PMID|20964792}} A role for endothelin receptor type A in migraine without aura susceptibility? A study in Portuguese patients.

{{PMID Auto
|PMID=23206929
|Title=Association study of multiple gene polymorphisms with the risk of adult-onset primary open-angle glaucoma in a Mexican population
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}