{{Rsnum
|rsid=5442
|Gene=GNB3
|Chromosome=12
|position=6845700
|Orientation=plus
|GMAF=0.03168
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=GNB3
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 15.0 | 84.1
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 2.0 | 98.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 2.0 | 98.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 3.4 | 96.6
| MKK | 0.0 | 0.0 | 0.0
| TSI | 1.0 | 7.8 | 91.2
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs5442
|Name_s=GNB3:814G>A; GNB3:Gly272Ser
|Gene_s=GNB3, USP5
|Feature=Exon/NonSyn, Intron
|Evidence=PubMed ID:1531240; PubMed ID:16908025
|Annotation=No association with coronary artery disease, myocardial infarction, diabetes, hypertension, or weight loss.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA161145078
}}

{{PMID Auto
|PMID=21174581
|Title=Genetic Variants, Endothelial Function, and Risk of Preeclampsia Among American Indians
}}

{{GET Evidence
|gene=GNB3
|aa_change=Gly272Ser
|aa_change_short=G272S
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs5442
|overall_frequency_n=567
|overall_frequency_d=10758
|overall_frequency=0.052705
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=6
|n_articles=0
|n_articles_annotated=0
|in_pharmgkb=Y
|pph2_score=0.184
|nblosum100=2
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}