{{Rsnum
|rsid=55754655
|Gene=AOX1
|Chromosome=2
|position=200661607
|Orientation=plus
|GMAF=0.107
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=AOX1
}}{{PharmGKB
|RSID=rs55754655
|Name_s=AOX1: c.3404A>G; Asn1135Ser
|Gene_s=AOX1
|Feature=Exon/NonSyn
|Evidence=PubMed ID:19500084
|Annotation=A study in a cohort of 192 patients receiving azathioprine for inflammatory bowel disease found that this SNP in the AOX1 gene predicted lack of azathioprine response (p=0.035, OR 2.54, 95%CI 1.06-6.13).
|Drugs=azathioprine
|Drug Classes=
|Diseases=Inflammatory Bowel Diseases
|Curation Level=Curated
|PharmGKB Accession ID=PA164925737
}}

{{PMID Auto
|PMID=22495427
|Title=Polymorphism of genes involved in purine metabolism (XDH, AOX1, MOCOS) in kidney transplant recipients receiving azathioprine.
}}

{{GET Evidence
|gene=AOX1
|aa_change=Asn1135Ser
|aa_change_short=N1135S
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs55754655
|overall_frequency_n=1871
|overall_frequency_d=10758
|overall_frequency=0.173917
|n_genomes=13
|n_genomes_annotated=0
|n_haplomes=15
|n_articles=1
|n_articles_annotated=1
|in_pharmgkb=Y
|nblosum100=0
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}