{{Rsnum
|rsid=560018
|Gene=GSTM4
|Chromosome=1
|position=109657738
|Orientation=minus
|GMAF=0.1887
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=GSTM4
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 39.6 | 47.7 | 12.6
| HCB | 89.6 | 9.6 | 0.7
| JPT | 93.3 | 6.7 | 0.0
| YRI | 80.7 | 19.3 | 0.0
| ASW | 81.8 | 18.2 | 0.0
| CHB | 89.6 | 9.6 | 0.7
| CHD | 90.7 | 9.3 | 0.0
| GIH | 79.2 | 19.8 | 1.0
| LWK | 83.5 | 14.7 | 1.8
| MEX | 60.3 | 36.2 | 3.4
| MKK | 69.5 | 29.2 | 1.3
| TSI | 44.9 | 48.0 | 7.1
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs560018
|Name_s=
|Gene_s=GSTM4
|Feature=
|Evidence=PubMed ID:20200426
|Annotation=Risk or phenotype-associated allele: not given. Phenotype: In lymphoblastoid cell lines, this SNP was significantly associated with the IC-50 of cisplatin. Study size/population/ethnicity: lymphoblastoid cell lines from 100 healthy Caucasian-American subjects. Significance metric(s): P = 0.019. Type of association: FA. Also, suggestive, but not significant, evidence was found for association of this SNP with survival of lung cancer patients treated with cisplatin.
|Drugs=cisplatin
|Drug Classes=
|Diseases=Lung Neoplasms
|Curation Level=Curated
|PharmGKB Accession ID=PA165291648
}}

{{PMID Auto
|PMID=17601350
|Title=A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
|OA=1
}}

{{PMID Auto
|PMID=19151192
|Title=Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs560018
|overall_frequency_n=3051
|overall_frequency_d=10758
|overall_frequency=0.283603
|n_genomes=20
|n_genomes_annotated=0
|n_haplomes=23
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}