{{Rsnum
|rsid=56149945
|Gene=NR3C1
|Chromosome=5
|position=143399752
|Orientation=plus
|GMAF=0.008264
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=NR3C1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 93.8 | 6.2 | 0.0
| HCB | 99.3 | 0.7 | 0.0
| JPT | 0.0 | 0.0 | 0.0
| YRI | 0.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 99.3 | 0.7 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 97.0 | 3.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 98.3 | 1.7 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
{{PMID Auto
|PMID=20440229
|Title=Glucocorticoid receptor gene polymorphisms in Italian patients with eating disorders and obesity
}}
{{omim
|id=138040
|rsnum=56149945
|variant=0007
}}{{ClinVar
|rsid=56149945
|Reversed=1
|FwdREF=A
|FwdALT=G,T
|REF=T
|ALT=A,C
|RSPOS=142779317
|CHROM=5
|GMAF=0.0082
|dbSNPBuildID=129
|SSR=0
|SAO=1
|VP=0x050178000000050516110100
|GENEINFO=NR3C1:2908
|GENE_NAME=NR3C1
|GENE_ID=2908
|WGT=0
|VC=SNV
|CLNALLE=2
|CLNHGVS=NC_000005.9:g.142779317T>C
|CLNORIGIN=1
|CLNSIG=2
|Tags=RV;PM;TPA;PMC;SLO;VLD;G5;HD;GNO;KGPhase1;KGPROD;OTHERKG;LSD;OM
|CAF=0.9917; 0.008264
|CLNACC=RCV000017532.1
|CLNDBN=GLUCOCORTICOID RECEPTOR POLYMORPHISM
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=138040.0007
|COMMON=1
|Disease=GLUCOCORTICOID RECEPTOR POLYMORPHISM
}}{{PMID Auto
|PMID=20712049
|Title=Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients.
|OA=1
}}{{GET Evidence
|gene=NR3C1
|aa_change=Asn363Ser
|aa_change_short=N363S
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs56149945
|overall_frequency_n=234
|overall_frequency_d=10758
|overall_frequency=0.0217513
|n_genomes=4
|n_genomes_annotated=0
|n_haplomes=5
|n_articles=0
|n_articles_annotated=0
|qualitycomment_in_silico=Y
|in_omim=Y
|pph2_score=0.001
|nblosum100=0
|autoscore=2
|webscore=N
}}{{PMID Auto
|PMID=23055001
|Title=Genetic evidence for the association of the hypothalamic-pituitary-adrenal (HPA) axis with ADHD and methylphenidate treatment response.
}}