{{Rsnum
|rsid=562338
|Chromosome=2
|position=21065449
|Orientation=minus
|GMAF=0.2461
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 64.6 | 26.5 | 8.8
| HCB | 97.8 | 2.2 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 10.9 | 37.4 | 51.7
| ASW | 24.6 | 43.9 | 31.6
| CHB | 97.8 | 2.2 | 0.0
| CHD | 99.1 | 0.9 | 0.0
| GIH | 77.2 | 18.8 | 4.0
| LWK | 15.5 | 50.0 | 34.5
| MEX | 70.7 | 27.6 | 1.7
| MKK | 24.4 | 48.1 | 27.6
| TSI | 62.7 | 33.3 | 3.9
| HapMapRevision=28
}}

Repeatedly associated with elevated lipids according to {{PMID|19161620|OA=1
}}

{{PMID Auto GWAS
|PMID=18262040
|Trait=LDL cholesterol
|Title=LDL-cholesterol concentrations: a genome-wide association study
|RiskAllele=T
|Pval=1.0000000000000001E-9
|OR=0.04
|ORtxt=[0.02-0.06] mmol/L decrease
|OA=1
}}
{{PMID Auto GWAS
|PMID=18193043
|Trait=LDL cholesterol
|Title=Newly identified loci that influence lipid concentrations and risk of coronary artery disease
|RiskAllele=G
|Pval=5.9999999999999998E-22
|OR=4.89
|ORtxt=[NR] mg/dl higher 	
}}

{{PMID|18179892|OA=1
}} Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.

{{PMID|18852197|OA=1
}} Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

{{PMID|19060910|OA=1
}} Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

{{PMID|21347282|OA=1
}} Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs562338
|overall_frequency_n=86
|overall_frequency_d=128
|overall_frequency=0.671875
|n_genomes=41
|n_genomes_annotated=0
|n_haplomes=69
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23150898
|Title=Evaluation of seven common lipid associated loci in a large Indian sib pair study
|OA=1
}}

{{PMID Auto
|PMID=23653095
|Title=Positive correlation between variants of lipid metabolism‑related genes and coronary heart disease
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}