{{Rsnum
|rsid=5628
|Gene=PTGIS
|Chromosome=20
|position=49524145
|Orientation=plus
|GMAF=0.1047
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=PTGIS
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 86.7 | 13.3 | 0.0
| HCB | 83.1 | 16.2 | 0.7
| JPT | 85.0 | 14.2 | 0.9
| YRI | 64.6 | 33.3 | 2.0
| ASW | 68.4 | 29.8 | 1.8
| CHB | 83.1 | 16.2 | 0.7
| CHD | 85.3 | 13.8 | 0.9
| GIH | 85.0 | 14.0 | 1.0
| LWK | 56.4 | 40.0 | 3.6
| MEX | 77.6 | 19.0 | 3.4
| MKK | 51.3 | 37.8 | 10.9
| TSI | 87.3 | 12.7 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs5628
|Name_s=PTGIS: 768G>A
|Gene_s=PTGIS
|Feature=
|Evidence=PubMed ID:11281454
|Annotation=This variant is the defining SNP for CYP8A1*3 haplotype.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA162355665
}}

{{PMID Auto
|PMID=21816595
|Title=A Promoter polymorphism (rs17222919, -1316T/G) of ALOX5AP is associated with intracerebral hemorrhage in Korean population
}}

{{PMID Auto
|PMID=19046748
|Title=Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs5628
|overall_frequency_n=1005
|overall_frequency_d=10758
|overall_frequency=0.0934189
|n_genomes=13
|n_genomes_annotated=0
|n_haplomes=15
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}