{{Rsnum
|rsid=563649
|Gene=OPRM1
|Chromosome=6
|position=154086832
|Orientation=minus
|GMAF=0.1042
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=OPRM1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 11.6 | 88.4
| HCB | 0.7 | 23.4 | 75.9
| JPT | 0.0 | 11.5 | 88.5
| YRI | 1.4 | 23.8 | 74.8
| ASW | 0.0 | 17.5 | 82.5
| CHB | 0.7 | 23.4 | 75.9
| CHD | 1.8 | 21.1 | 77.1
| GIH | 0.0 | 18.8 | 81.2
| LWK | 0.9 | 12.7 | 86.4
| MEX | 6.9 | 34.5 | 58.6
| MKK | 0.0 | 13.5 | 86.5
| TSI | 2.0 | 21.6 | 76.5
| HapMapRevision=28
}}{{omim
|desc=OPIOID RECEPTOR, MU-1; OPRM1
|id=600018
|rsnum=563649
}}

{{PharmGKB
|RSID=rs563649
|Name_s=
|Gene_s=OPRM1
|Feature=
|Evidence=PubMed ID:19103668
|Annotation=This SNP within a structurally conserved internal ribosomal binding site in the 5'UTR of a novel exon 13-containig OPRM1 isoform was strong associated with individual variations in pain perception.
|Drugs=
|Drug Classes=
|Diseases=Pain
|Curation Level=Curated
|PharmGKB Accession ID=PA162364099
}}

{{PMID|18433502|OA=1
}} Association between single nucleotide polymorphisms in the mu opioid receptor gene (OPRM1) and self-reported responses to alcohol in American Indians.

{{PMID|19775452|OA=1
}} Do genetic predictors of pain sensitivity associate with persistent widespread pain?

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs563649
|overall_frequency_n=12
|overall_frequency_d=128
|overall_frequency=0.09375
|n_genomes=11
|n_genomes_annotated=0
|n_haplomes=12
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=22406240
|Title=Genetic polymorphisms in the opioid receptor mu1 gene are associated with changes in libido and insomnia in methadone maintenance patients.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}