{{Rsnum
|rsid=563694
|Chromosome=2
|position=169774071
|Orientation=minus
|GMAF=0.1846
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}
{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 13.3 | 47.8 | 38.9
| HCB | 0.0 | 3.7 | 96.3
| JPT | 0.0 | 7.1 | 92.9
| YRI | 0.7 | 7.5 | 91.8
| ASW | 0.0 | 15.8 | 84.2
| CHB | 0.0 | 3.7 | 96.3
| CHD | 0.0 | 8.3 | 91.7
| GIH | 4.0 | 29.0 | 67.0
| LWK | 0.0 | 4.6 | 95.4
| MEX | 1.7 | 34.5 | 63.8
| MKK | 0.0 | 14.3 | 85.7
| TSI | 13.0 | 39.0 | 48.0
| HapMapRevision=28
}}{{GWAS Summary
|SNP=rs563694
|PubMedID=18521185
|Condition=Fasting plasma glucose
|Gene=G6PC2,ABCB11
|Risk Allele=C
|pValue=4.00E-007
|OR=NA
|95CI=
|OA=1
}}

{{omim
|desc=FASTING PLASMA GLUCOSE LEVEL QUANTITATIVE TRAIT LOCUS 1; FGQTL1
|id=612108
|rsnum=563694
}}

{{PharmGKB
|RSID=rs563694
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:18521185; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels (Initial Sample Size: 5,088 nondiabetic individuals; Replication Sample Size: 18,436 nondiabetic individuals; Risk Allele: rs563694-C). This variant is associated with Fasting plasma glucose.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356587
}}

{{PMID Auto
|PMID=18852197
|Title=Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
|OA=1
}}

{{PMID Auto
|PMID=18984742
|Title=A single-nucleotide polymorphism in a methylatable Foxa2 binding site of the G6PC2 promoter is associated with insulin secretion in vivo and increased promoter activity in vitro.
|OA=1
}}

{{PMID Auto
|PMID=19060907
|Title=Variants in MTNR1B influence fasting glucose levels.
|OA=1
}}

{{PMID Auto
|PMID=19096518
|Title=Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.
|OA=1
}}

{{PMID Auto
|PMID=19197348
|Title=Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
|OA=1
}}

{{PMID Auto
|PMID=19679263
|Title=Using new tools to define the genetic underpinnings of risky traits associated with coronary artery disease: the SardiNIA study.
|OA=1
}}

{{PMID Auto
|PMID=20628598
|Title=Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting plasma glucose and impaired beta-cell function in Chinese subjects.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs563694
|overall_frequency_n=102
|overall_frequency_d=128
|overall_frequency=0.796875
|n_genomes=51
|n_genomes_annotated=0
|n_haplomes=87
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}