{{Rsnum
|rsid=5743289
|Gene=NOD2
|Chromosome=16
|position=50722863
|Orientation=plus
|GMAF=0.07668
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=NOD2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 57.5 | 39.8 | 2.7
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 89.5 | 7.0 | 3.5
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 99.0 | 1.0 | 0.0
| LWK | 97.3 | 2.7 | 0.0
| MEX | 77.6 | 22.4 | 0.0
| MKK | 86.5 | 12.8 | 0.6
| TSI | 68.6 | 29.4 | 2.0
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=18758464
|Trait=Inflammatory bowel disease
|Title=Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease
|RiskAllele=T
|Pval=4.0000000000000001E-10
|OR=1.46
|ORtxt=[1.29-1.64]
|OA=1
}}
{{PMID Auto GWAS
|PMID=17804789
|Trait=Crohn's disease
|Title=Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci
|RiskAllele=
|Pval=6.0000000000000001E-17
|OR=NR
|ORtxt=NR
|OA=1
}}
{{PMID Auto GWAS
|PMID=17447842
|Trait=Crohn's disease
|Title=Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
|RiskAllele=
|Pval=9.9999999999999995E-7
|OR=NR
|ORtxt=NR
|OA=1
}}

{{PMID Auto
|PMID=17068223
|Title=A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.
}}

{{PMID Auto
|PMID=19843337
|Title=Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs5743289
|overall_frequency_n=12
|overall_frequency_d=128
|overall_frequency=0.09375
|n_genomes=9
|n_genomes_annotated=0
|n_haplomes=11
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
|summary_short=rs5743289 is a C/T variation in the NOD2 gene (intronic) on human chromosome 16, associated with Crohn's disease.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}