{{Rsnum
|rsid=5743551
|Gene=TLR1
|Chromosome=4
|position=38806033
|Orientation=minus
|GMAF=0.4651
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=TLR1
}}{{PMID|18635889|OA=1
}}  excessive inflammation during an infection and contribute to an increased risk for poor outcomes in patients with sepsis

G allele of TLR1-7202A/G (rs5743551)

associations with death, organ dysfunction

associated with elevated TLR1-mediated cytokine production (P < 2x10(-20))

predicted worse organ dysfunction and death (OR 1.82, 95% CI 1.07-3.09). 

sepsis-related ALI (OR 3.40, 95% CI 1.59-7.27)

and gram-positive infection in sepsis.

{{PMID Auto
|PMID=18396467
|Title=Genetic variation and haplotype structures of innate immunity genes in eastern India.
|OA=1
}}

{{PMID Auto
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{{PMID Auto
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|Title=Family-based samples can play an important role in genetic association studies.
|OA=1
}}

{{PMID Auto
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|Title=Toll-like receptor signaling pathway variants and prostate cancer mortality.
|OA=1
}}

{{PMID Auto
|PMID=20200442
|Title=Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.
|OA=1
}}

{{PMID Auto
|PMID=21274447
|Title=Genetic polymorphisms and posttraumatic complications.
|OA=1
}}

{{PMID Auto
|PMID=21872627
|Title=Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.
}}

{{PMID Auto
|PMID=23478521
|Title=Toll-Like Receptor 1 Polymorphisms and Associated Outcomes in Sepsis After Traumatic Injury: A Candidate Gene Association Study
}}

{{PMID Auto
|PMID=25128583
|Title=Association of TLR and TREM-1 Gene Polymorphisms with Risk of Coronary Artery Disease in a Russian Population
}}

{{PMID Auto
|PMID=25213166
|Title=An association between single nucleotide polymorphisms within TLR and TREM-1 genes and infective endocarditis
}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}