{{Rsnum
|rsid=5744174
|Gene=TLR5
|Chromosome=1
|position=223111186
|Orientation=minus
|GMAF=0.2759
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=TLR5
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 18.8 | 46.4 | 34.8
| HCB | 4.4 | 31.4 | 64.2
| JPT | 1.8 | 25.9 | 72.3
| YRI | 0.7 | 17.0 | 82.3
| ASW | 0.0 | 38.6 | 61.4
| CHB | 4.4 | 31.4 | 64.2
| CHD | 3.7 | 37.6 | 58.7
| GIH | 24.8 | 58.4 | 16.8
| LWK | 3.7 | 22.0 | 74.3
| MEX | 15.8 | 38.6 | 45.6
| MKK | 4.5 | 30.1 | 65.4
| TSI | 12.9 | 55.4 | 31.7
| HapMapRevision=28
}}{{PMID Auto
|PMID=21994405
|Title=Genetic Variants of Toll-Like Receptor 2 and 5, Helicobacter pylori Infection, and Risk of Gastric Cancer and Its Precursors in a Chinese Population
}}

{{PMID|16846490|OA=1
}} Lemierre's syndrome and genetic polymorphisms: a case report.

{{PMID|18325643|OA=1
}} Associations between SNPs in toll-like receptors and related intracellular signaling molecules and immune responses to measles vaccine: preliminary results.

{{PMID|18396467|OA=1
}} Genetic variation and haplotype structures of innate immunity genes in eastern India.

{{PMID|19505919|OA=1
}} Toll-like receptor signaling pathway variants and prostate cancer mortality.

{{PMID|19543401|OA=1
}} Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.

{{GET Evidence
|gene=TLR5
|aa_change=Phe616Leu
|aa_change_short=F616L
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs5744174
|overall_frequency_n=3591
|overall_frequency_d=10758
|overall_frequency=0.333798
|n_genomes=24
|n_genomes_annotated=0
|n_haplomes=28
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.011
|nblosum100=0
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23593463
|Title=A Non-Synonymous Coding Variant (L616F) in the TLR5 Gene Is Potentially Associated with Crohn's Disease and Influences Responses to Bacterial Flagellin
|OA=1
}}

{{PMID Auto
|PMID=22740716
|Title=Toll-like receptor and hepatitis B virus clearance in chronic infected patients: a long-term prospective cohort study in Taiwan.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}