{{Rsnum
|rsid=5748469
|Gene=TXNRD2
|Chromosome=22
|position=19919576
|Orientation=plus
|GMAF=0.4894
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=TXNRD2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 11.6 | 42.9 | 45.5
| HCB | 69.3 | 29.2 | 1.5
| JPT | 72.6 | 25.7 | 1.8
| YRI | 4.9 | 31.2 | 63.9
| ASW | 5.3 | 45.6 | 49.1
| CHB | 69.3 | 29.2 | 1.5
| CHD | 78.9 | 19.3 | 1.8
| GIH | 21.8 | 48.5 | 29.7
| LWK | 11.0 | 31.2 | 57.8
| MEX | 37.9 | 46.6 | 15.5
| MKK | 3.2 | 33.8 | 63.0
| TSI | 14.0 | 43.0 | 43.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20178852
|Title=Association Study between Polymorphisms in Selenoprotein Genes and Susceptibility to Kashin-Beck Disease
}}

{{PMID Auto
|PMID=17601350
|Title=A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
|OA=1
}}

{{GET Evidence
|gene=TXNRD2
|aa_change=Ala66Ser
|aa_change_short=A66S
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs5748469
|overall_frequency_n=3087
|overall_frequency_d=10346
|overall_frequency=0.298376
|n_genomes=3
|n_genomes_annotated=0
|n_haplomes=4
|n_articles=0
|n_articles_annotated=0
|nblosum100=-1
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=24058403
|Title=Association study of polymorphisms in selenoprotein genes and Kashin-Beck disease and serum selenium/iodine concentration in a Tibetan population
}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}