{{Rsnum
|rsid=5771069
|Gene=IL17REL
|Chromosome=22
|position=49997051
|Orientation=plus
|GMAF=0.4435
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=IL17REL
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 17.7 | 55.8 | 26.5
| HCB | 15.3 | 48.2 | 36.5
| JPT | 22.1 | 53.1 | 24.8
| YRI | 11.6 | 49.0 | 39.5
| ASW | 14.0 | 54.4 | 31.6
| CHB | 15.3 | 48.2 | 36.5
| CHD | 21.1 | 39.4 | 39.4
| GIH | 3.0 | 31.7 | 65.3
| LWK | 9.1 | 39.1 | 51.8
| MEX | 25.9 | 53.4 | 20.7
| MKK | 14.1 | 40.4 | 45.5
| TSI | 17.6 | 54.9 | 27.5
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20228798
|Trait=Ulcerative colitis
|Title=Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)
|RiskAllele=G
|Pval=4E-8
|OR=1.17
|ORtxt=[1.11-1.25]
}}

{{omim
|id=266600
|rsnum=5771069
}}

{{PMID Auto GWAS
|PMID=21297633
|Trait=None
|Title=Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
|RiskAllele=G
|Pval=2E-7
|OR=1.1100
|ORtxt=[1.07-1.16]
|OA=1
}}

{{PMID Auto
|PMID=21995314
|Title=Assessment of heterogeneity between European Populations: a Baltic and Danish replication case-control study of SNPs from a recent European ulcerative colitis genome wide association study
|OA=1
}}

{{GET Evidence
|gene=IL17REL
|aa_change=Leu333Pro
|aa_change_short=L333P
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs5771069
|overall_frequency_n=5761
|overall_frequency_d=10706
|overall_frequency=0.538109
|n_genomes=49
|n_genomes_annotated=0
|n_haplomes=69
|n_articles=0
|n_articles_annotated=0
|nblosum100=7
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}