{{Rsnum
|rsid=5880
|Gene=CETP
|Chromosome=16
|position=56981179
|Orientation=plus
|GMAF=0.03398
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=CETP
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 0.0 | 9.2 | 90.8
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs5880
|Name_s=
|Gene_s=CETP
|Feature=Exon/NonSyn
|Evidence=PubMed ID:17952847
|Annotation=This SNP has been associated with small changes in HDL cholesterol levels. The C allele has been correlated with lower HDL.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA161613796
}}

{{PMID Auto
|PMID=12475937
|Title=Association testing by DNA pooling: an effective initial screen.
|OA=1
}}

{{PMID Auto
|PMID=12802015
|Title=Direct molecular haplotyping of long-range genomic DNA with M1-PCR.
|OA=1
}}

{{PMID Auto
|PMID=16700901
|Title=Physiogenomic analysis of weight loss induced by dietary carbohydrate restriction.
|OA=1
}}

{{PMID Auto
|PMID=18254975
|Title=Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat.
|OA=1
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{PMID Auto
|PMID=19802338
|Title=Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.
|OA=1
}}

{{PMID Auto
|PMID=19913121
|Title=Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
|OA=1
}}

{{PMID Auto
|PMID=20031564
|Title=Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.
|OA=1
}}

{{GET Evidence
|gene=CETP
|aa_change=Ala390Pro
|aa_change_short=A390P
|impact=pathogenic
|qualified_impact=Low clinical importance, Likely pathogenic
|inheritance=undefined
|quality_scores=Array
|dbsnp_id=rs5880
|overall_frequency_n=418
|overall_frequency_d=10758
|overall_frequency=0.0388548
|n_genomes=4
|n_genomes_annotated=0
|n_haplomes=4
|n_articles=1
|n_articles_annotated=1
|qualityscore_in_silico=2
|qualitycomment_in_silico=Y
|qualityscore_case_control=4
|qualitycomment_case_control=Y
|qualityscore_familial=0
|qualitycomment_familial=Y
|qualityscore_severity=3
|qualitycomment_severity=Y
|qualityscore_treatability=3
|qualitycomment_treatability=Y
|gene_in_genetests=Y
|in_pharmgkb=Y
|pph2_score=0.992
|genetests_testable=Y
|nblosum100=2
|autoscore=5
|webscore=N
|n_web_uneval=3
|variant_evidence=0
|clinical_importance=1
|summary_short=This variant is associated with slightly lower HDL (good) cholesterol, although it has a negligible effect (around 2 mg/dl).
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}