{{Rsnum
|rsid=588765
|Gene=CHRNA5
|Chromosome=15
|position=78573083
|Orientation=plus
|GMAF=0.2759
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CHRNA5
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 44.3 | 39.3 | 16.4
| HCB | 79.1 | 16.3 | 4.7
| JPT | 77.3 | 22.7 | 0.0
| YRI | 65.5 | 31.0 | 3.4
| ASW | 0.0 | 0.0 | 0.0
| CHB | 79.1 | 16.3 | 4.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=19706806
|Title=A Novel Polymorphism rs1329149 of CYP2E1 and a Known Polymorphism rs671 of ALDH2 of Alcohol Metabolizing Enzymes Are Associated with Colorectal Cancer in a Southwestern Chinese Population
}}
{{PMID Auto
|PMID=19706810
|Title=Variants Weakly Correlated with CHRNA5 D398N Polymorphism Should be Considered in Transcriptional Deregulation at the 15q25 Locus Associated with Lung Cancer Risk
}}
{{PMID Auto
|PMID=20700436
|Title=Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD
|OA=1
}}

{{omim
|desc=CHOLINERGIC RECEPTOR, NEURONAL NICOTINIC, ALPHA POLYPEPTIDE 5; CHRNA5
|id=118505
|rsnum=588765
}}

{{PMID Auto
|PMID=19029397
|Title=Nicotinic receptor gene variants influence susceptibility to heavy smoking.
|OA=1
}}

{{PMID Auto
|PMID=19443489
|Title=Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
|OA=1
}}

{{PMID Auto
|PMID=19706762
|Title=The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
|OA=1
}}

{{PMID Auto
|PMID=23249876
|Title=Nicotinic acetylcholine receptor variation and response to smoking cessation therapies
|OA=1
}}

{{PMID Auto
|PMID=22884254
|Title=Association of nicotine dependence susceptibility gene, CHRNA5, with Parkinson's disease age at onset: gene and smoking status interaction.
}}

{{PMID Auto
|PMID=23011884
|Title=Functional effect of polymorphisms in 15q25 locus on CHRNA5 mRNA, bulky DNA adducts and TP53 mutations.
}}

{{PMID Auto
|PMID=23404318
|Title=Interpreting joint SNP analysis results: when are two distinct signals really two distinct signals?
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}