{{Rsnum
|rsid=59328451
|Gene=KRT16
|Chromosome=17
|position=41610549
|Orientation=minus
|GMAF=0.0004591
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=KRT16
}}This SNP has been found in patients with [[pachyonychia congenita Type I]], and the risk allele appears to be a causative mutation for this (dominant) disorder.

See also: [http://www.ncbi.nlm.nih.gov/omim/148067?db=omim&dopt=Detailed#148067Variants0008 OMIM 148067.0008]

{{omim
|id=148067
|rsnum=59328451
|variant=0008
}}

{{ClinVar
|rsid=59328451
|Reversed=1
|FwdREF=A
|FwdALT=T
|REF=T
|ALT=A
|RSPOS=39766801
|CHROM=17
|GMAF=0.0005
|dbSNPBuildID=133
|SSR=0
|SAO=1
|VP=0x050360000000040016110100
|GENEINFO=KRT16:3868
|GENE_NAME=KRT16
|GENE_ID=3868
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000017.10:g.39766801T>A
|CLNORIGIN=1
|CLNSIG=5
|Tags=RV;PM;S3D;SLO;VLD;KGPhase1;KGPROD;OTHERKG;LSD;OM
|CAF=0.9995; 0.0004591
|CLNACC=RCV000015711.24; RCV000057025.1
|CLNDBN=Pachyonychia congenita tarda, type 1; not provided
|CLNSRC=Epithelial Biology; OMIM Allelic Variant
|CLNSRCID=KRT16:c.1062A>T; 148067.0008
|COMMON=0
|Disease=Pachyonychia congenita tarda; not provided
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}