{{Rsnum
|rsid=5985
|Gene=F13A1
|Chromosome=6
|position=6318562
|Orientation=minus
|GMAF=0.1566
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=F13A1
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 61.6 | 34.8 | 3.6
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 69.4 | 28.6 | 2.0
| ASW | 73.7 | 22.8 | 3.5
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 85.1 | 13.9 | 1.0
| LWK | 65.5 | 33.6 | 0.9
| MEX | 56.9 | 39.7 | 3.4
| MKK | 81.4 | 17.3 | 1.3
| TSI | 56.9 | 35.3 | 7.8
| HapMapRevision=28
}}{{omim
|id=134570
|rsnum=5985
|variant=0010
}}

{{PMID Auto
|PMID=21332313
|Title=Sequence variations in the FII, FV, F13A1, FGB and PAI-1 genes are associated with differences in myocardial perfusion
}}

{{PMID Auto
|PMID=21913742
|Title=Genetic predictors of response to photodynamictherapy
}}

{{ClinVar
|rsid=5985
|Reversed=1
|FwdREF=G
|FwdALT=T
|REF=C
|ALT=A
|RSPOS=6318795
|CHROM=6
|GMAF=0.1566
|dbSNPBuildID=52
|SSR=0
|SAO=1
|VP=0x05036800000015051f130101
|GENEINFO=F13A1:2162
|GENE_NAME=F13A1
|GENE_ID=2162
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000006.11:g.6318795C>A
|CLNORIGIN=1
|CLNSIG=255
|Tags=RV;PM;PMC;S3D;SLO;VLD;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD;MTP;OM
|CAF=0.8434; 0.1566
|CLNACC=RCV000017996.1; RCV000017997.1
|CLNDBN=Myocardial infarction, protection against; Venous thrombosis, protection against
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=134570.0010
|COMMON=1
|Disease=Myocardial infarction; Venous thrombosis
}}

{{PMID|16525568}} Epistatic and pleiotropic effects of polymorphisms in the fibrinogen and coagulation factor XIII genes on plasma fibrinogen concentration, fibrin gel structure and risk of myocardial infarction.

{{PMID|16681647|OA=1
}} Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway.

{{PMID|17107626|OA=1
}} Comparison of PrASE and Pyrosequencing for SNP Genotyping.

{{PMID|17241179}} The association between fibrinogen haplotypes and myocardial infarction in men is partly mediated through pleiotropic effects on the serum IL-6 concentration.

{{PMID|20031584|OA=1
}} Genetics of atherothrombotic and lacunar stroke.

{{PMID|20532202|OA=1
}} Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.

{{PMID|20887247}} Pharmacogenetic aspects in therapeutic management of subfoveal choroidal neovascularisation: role of factor XIII-A 185 T-allele.

{{PMID|21422408}} Clotting factor gene polymorphisms and colorectal cancer risk.

{{PMID|22267327}} Fibrinogen and factor XIII A-subunit genotypes interactively influence C-reactive protein levels during inflammation.

{{GET Evidence
|gene=F13A1
|aa_change=Val35Leu
|aa_change_short=V35L
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs5985
|overall_frequency_n=2443
|overall_frequency_d=10758
|overall_frequency=0.227087
|n_genomes=12
|n_genomes_annotated=0
|n_haplomes=13
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|nblosum100=0
|autoscore=2
|n_web_uneval=1
}}

{{PMID Auto
|PMID=23381943
|Title=Ischemic stroke is associated with the ABO locus: The EuroCLOT study
|OA=1
}}

{{PMID Auto
|PMID=22909824
|Title=Activity and levels of factor XIII in a Venezuelan admixed population: association with rs5985 (Val35Leu) and STR F13A01 polymorphisms.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}