{{Rsnum
|rsid=5988
|Gene=F13A1
|Chromosome=6
|position=6151904
|Orientation=minus
|ReferenceAllele=G
|MissenseAllele=C
|GMAF=0.1882
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=F13A1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 1.5 | 43.1 | 55.4
| HCB | 2.2 | 13.3 | 84.4
| JPT | 0.0 | 18.2 | 81.8
| YRI | 4.8 | 41.3 | 54.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 2.2 | 13.3 | 84.4
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

{{Venter SNP
|rsid=5988
|allele=G
|frequency=0.225
|uid=1103652773022
|type=homozygous_SNP
|hugo=F13A1
|ensembl gene=ENSG00000124491
|ensembl transcript=ENST00000264870
|sift=TOLERATED
|disease=Defects in F13A1 are the cause of F13A deficiency (MIM:134570). F13A deficiency is an autosomal recessive disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women. In addition to the common presentation such as subcutaneous and intramuscular haematomas, severe bleeding such as intracranial hemorrhages may occur.
}}

{{ neighbor
| rsid = 5987
| distance = 3
}}

{{PMID|19552680|OA=1
}} Common hemostasis and inflammation gene variants and venous thrombosis in older adults from the Cardiovascular Health Study.

{{GET Evidence
|gene=F13A1
|aa_change=Glu652Gln
|aa_change_short=E652Q
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs5988
|overall_frequency_n=2342
|overall_frequency_d=10758
|overall_frequency=0.217698
|n_genomes=18
|n_genomes_annotated=0
|n_haplomes=20
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|nblosum100=-2
|autoscore=2
|n_web_uneval=3
}}

{{on chip | HumanOmni1Quad}}