{{Rsnum
|rsid=5993882
|Gene=COMT
|Chromosome=22
|position=19950010
|Orientation=plus
|GMAF=0.2433
|Gene_s=COMT
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 2.7 | 42.5 | 54.9
| HCB | 1.5 | 20.4 | 78.1
| JPT | 0.0 | 31.2 | 68.8
| YRI | 11.7 | 48.3 | 40.0
| ASW | 14.0 | 49.1 | 36.8
| CHB | 1.5 | 20.4 | 78.1
| CHD | 0.0 | 18.3 | 81.7
| GIH | 7.9 | 42.6 | 49.5
| LWK | 17.4 | 45.0 | 37.6
| MEX | 3.4 | 31.0 | 65.5
| MKK | 10.3 | 45.5 | 44.2
| TSI | 5.9 | 46.1 | 48.0
| HapMapRevision=28
}}This is one of the SNPs reported by [[NutraHacker SNPs|NutraHacker]].

{{PMID Auto
|PMID=16848906
|Title=Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans.
|OA=1
}}

{{PMID Auto
|PMID=18574484
|Title=The complex global pattern of genetic variation and linkage disequilibrium at catechol-O-methyltransferase.
|OA=1
}}

{{PMID Auto
|PMID=19772600
|Title=A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data.
|OA=1
}}

{{PMID Auto
|PMID=22337325
|Title=The effect of catechol-O-methyltransferase polymorphisms on pain is modified by depressive symptoms.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}