{{Rsnum
|rsid=6003
|Gene=F13B
|Chromosome=1
|position=197061891
|Orientation=minus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.1938
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=F13B
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 83.0 | 17.0 | 0.0
| HCB | 95.6 | 4.4 | 0.0
| JPT | 95.6 | 4.4 | 0.0
| YRI | 7.1 | 39.7 | 53.2
| ASW | 17.5 | 59.6 | 22.8
| CHB | 95.6 | 4.4 | 0.0
| CHD | 96.3 | 3.7 | 0.0
| GIH | 76.2 | 19.8 | 4.0
| LWK | 16.4 | 53.6 | 30.0
| MEX | 87.7 | 12.3 | 0.0
| MKK | 26.3 | 47.4 | 26.3
| TSI | 85.3 | 13.7 | 1.0
| HapMapRevision=28
}}

{{Venter SNP
|rsid=6003
|allele=T
|frequency=0.075
|uid=1103675303724
|type=heterozygous_SNP
|hugo=F13B
|ensembl gene=ENSG00000143278
|ensembl transcript=ENST00000271509
|sift=TOLERATED
|disease=Defects in F13B can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.
}}

{{omim
|id=134580
|rsnum=6003
|variant=0003
}}

{{ClinVar
|rsid=6003
|Reversed=1
|FwdREF=G
|FwdALT=A
|REF=C
|ALT=T
|RSPOS=197061891
|CHROM=1
|GMAF=0.1941
|dbSNPBuildID=52
|SSR=0
|SAO=1
|VP=0x050368080a1515051f130101
|GENEINFO=F13B:2165
|GENE_NAME=F13B
|GENE_ID=2165
|WGT=1
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000001.11:g.197061891C>T
|CLNORIGIN=1
|CLNSIG=255
|Tags=RV;PM;PMC;S3D;SLO;NSM;REF;INT;OTH;ASP;VLD;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD;MTP;OM
|CAF=0.1938; 0.8062
|CLNACC=RCV000017984.1
|CLNDBN=Venous thrombosis, susceptibility to
|CLNSRC=ClinVar; OMIM Allelic Variant
|CLNSRCID=NM_001994.2:c.344G>A; 134580.0003
|COMMON=1
|Disease=Venous thrombosis
}}

{{PMID Auto
|PMID=15660291
|Title=Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study.
|OA=1
}}

{{PMID Auto
|PMID=18541031
|Title=The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.
|OA=1
}}

{{PMID Auto
|PMID=18654799
|Title=Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease.
|OA=1
}}

{{PMID Auto
|PMID=20021678
|Title=Evaluation of self-reported ethnicity in a case-control population: the stroke prevention in young women study.
|OA=1
}}

{{GET Evidence
|gene=F13B
|aa_change=Arg115His
|aa_change_short=R115H
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6003
|overall_frequency_n=7912
|overall_frequency_d=10758
|overall_frequency=0.735453
|n_genomes=47
|n_genomes_annotated=0
|n_haplomes=76
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|pph2_score=0.006
|genetests_testable=Y
|nblosum100=1
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23582991
|Title=Genetic Influences on the Outcome of Anti-Vascular Endothelial Growth Factor Treatment in Neovascular Age-related Macular Degeneration
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}