{{Rsnum
|rsid=6019
|Gene=F5
|Chromosome=1
|position=169572275
|Orientation=minus
|ReferenceAllele=G
|MissenseAllele=C
|GMAF=0.1084
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=F5
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 0.0 | 9.2 | 90.8
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 12.7 | 52.4 | 34.9
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID|19020903}} [[rs6019]] and [[rs6022]] maternal [[smoking]] on PTD and gestational age. Compared with non-smoking mothers carrying rs6019(C) associated with significantly increased risk of PTD (OR(95% CI): 2.1(1.2-3.6) for GC; 5.7(2.1-15.0) for CC; p-interaction = 0.02

{{PMID Auto
|PMID=22281051
|Title=Association of Factor V Gene Polymorphism With Arteriovenous Graft Failure
|OA=1
}}

{{PMID|16642433|OA=1
}} Polymorphism in maternal LRP8 gene is associated with fetal growth.

{{GET Evidence
|gene=F5
|aa_change=Asp107His
|aa_change_short=D107H
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6019
|overall_frequency_n=1692
|overall_frequency_d=10756
|overall_frequency=0.157308
|n_genomes=14
|n_genomes_annotated=0
|n_haplomes=19
|n_articles=0
|n_articles_annotated=0
|qualityscore_in_silico=3
|qualitycomment_in_silico=Y
|gene_in_genetests=Y
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=3
|autoscore=3
|n_web_uneval=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}