{{Rsnum
|rsid=605059
|Gene=HSD17B1
|Chromosome=17
|position=42554888
|Orientation=minus
|GMAF=0.4871
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=HSD17B1
}}{{PMID Auto
|PMID=20432167
|Title=Dietary isoflavone intake, polymorphisms in the CYP17, CYP19, 17beta-HSD1, and SHBG genes, and risk of breast cancer in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians
}}

{{PMID Auto
|PMID=20586553
|Title=Polymorphisms in ESR1, ESR2 and HSD17B1 genes are associated with fertility status in endometriosis
}}

{{PMID|16489054}} Haplotype analysis of the HSD17B1 gene and risk of breast cancer: a comprehensive approach to multicenter analyses of prospective cohort studies.

{{PMID|17301695|OA=1
}} Interaction of soy and 17beta-HSD1 gene polymorphisms in the risk of endometrial cancer.

{{PMID|18086758|OA=1
}} Association between single-nucleotide polymorphisms in hormone metabolism and DNA repair genes and epithelial ovarian cancer: results from two Australian studies and an additional validation set.

{{PMID|18483327|OA=1
}} Polymorphisms in steroid hormone biosynthesis genes and risk of breast cancer and fibrocystic breast conditions in Chinese women.

{{PMID|18805939|OA=1
}} Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.

{{PMID|18843021|OA=1
}} HSD17B1 genetic variants and hormone receptor-defined breast cancer.

{{PMID|19015200|OA=1
}} Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer.

{{PMID|19679043|OA=1
}} African American-preponderant single nucleotide polymorphisms (SNPs) and risk of breast cancer.

{{PMID|21429951}} Quantitative trait analysis suggests polymorphisms of estrogen-related genes regulate human sperm concentrations and motility.

{{PMID|22546946}} Polymorphisms in genes HSD17B1 and HSD17B2 and uterine leiomyoma risk in Chinese women.

{{GET Evidence
|gene=HSD17B1
|aa_change=Gly313Ser
|aa_change_short=G313S
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs605059
|overall_frequency_n=5557
|overall_frequency_d=9302
|overall_frequency=0.597398
|n_genomes=37
|n_genomes_annotated=0
|n_haplomes=54
|n_articles=0
|n_articles_annotated=0
|nblosum100=2
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23430226
|Title=Confirmation of the reduction of hormone replacement therapy-related breast cancer risk for carriers of the HSD17B1_937_G variant.
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}