{{Rsnum
|rsid=6065
|Gene=GP1BA
|Chromosome=17
|position=4933086
|Orientation=plus
|GMAF=0.1295
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=GP1BA
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 89.4 | 10.6 | 0.0
| HCB | 90.4 | 9.6 | 0.0
| JPT | 74.1 | 24.1 | 1.8
| YRI | 61.2 | 30.6 | 8.2
| ASW | 54.4 | 36.8 | 8.8
| CHB | 90.4 | 9.6 | 0.0
| CHD | 90.8 | 9.2 | 0.0
| GIH | 87.1 | 10.9 | 2.0
| LWK | 49.5 | 45.9 | 4.6
| MEX | 81.0 | 17.2 | 1.7
| MKK | 51.6 | 42.6 | 5.8
| TSI | 88.0 | 11.0 | 1.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20139978
|Trait=Hematological and biochemical traits
|Title=Genome-wide association study of hematological and biochemical traits in a Japanese population
|RiskAllele=T
|Pval=2E-12
|OR=0.33
|ORtxt=[NR] % variance
}}

{{PMID Auto
|PMID=20472470
|Title=Impact of COX-2 rs5275 and rs20417 and GPIIIa rs5918 Polymorphisms on 90-Day Ischemic Stroke Functional Outcome: A Novel Finding
}}

{{PharmGKB
|RSID=rs6065
|Name_s=GP1BA: ?5T>C
|Gene_s=RNF167, GP1BA
|Feature=
|Evidence=PubMed ID:19740098
|Annotation=Risk or phenotype-associated allele: C. Phenotype: An in vitro PFA-100 analysis was performed within 4 h of phlebotomy (blood drawn from healthy volunteers), using CADP and CEPI cartridges. GP1BA: -5T>C significantly effected platelet responses to collagen plus ADP (CADP). After accounting for multiple testing (Bonferroni adjustment), a statistically significant inverse correlation remained between CADP CT and GP1BA -5C (adjusted P = 0.011).
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA165291886
}}

{{PMID Auto
|PMID=22133274
|Title=Polymorphisms of PAI-1 and platelet GP Ia may associate with impairment of renal function and thrombocytopenia in Puumala hantavirus infection
|OA=1
}}

{{PMID Auto
|PMID=18403734
|Title=Polymorphisms in platelet glycoprotein 1balpha and factor VII and risk of ischemic stroke: a meta-analysis.
}}

{{PMID Auto
|PMID=22388798
|Title=Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.
|OA=1
}}

{{GET Evidence
|gene=GP1BA
|aa_change=Thr161Met
|aa_change_short=T161M
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6065
|overall_frequency_n=1228
|overall_frequency_d=10064
|overall_frequency=0.122019
|n_genomes=15
|n_genomes_annotated=0
|n_haplomes=16
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|nblosum100=2
|autoscore=1
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=22139419
  |Trait=Platelet counts
  |Title=New gene functions in megakaryopoiesis and platelet formation.
  |RiskAllele=T
  |Pval=3E-11
  |OR=4.19
  |ORtxt=[2.96-5.43] 10^9/l increase
  |OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}